Botox was the original and has become a generic term, but these two brands work by very similar mechanisms. Simply put, when you inject them, they block the signal going between the nerves going to the muscle, so the muscle can’t cause wrinkles. So who wins the Botox Vs Dysport battle?

It depends... there are some subtle differences. Here's what they are:

Dysport and Botox are both derived from Clostridium botulinum bacteria, which produces botulinum toxin. Dysport and Botox work by relaxing the muscles which repetitively contract, leading to the formation of deep wrinkles and folds on the forehead and in between the eyes.

The main difference between Dysport and Botox lies in the complexities of their accessory proteins, which results in potency variations of their trace proteins.


Dysport has a quicker onset of 2-5 days vs Botox which takes about 5-10 days. This is because Dysport has a more diluted concentration than Botox, which affects the dosage volume for every treatment. If you've got an event coming up, you're probably going to want Dysport. On a side note, Dysport also wears off more slowly, Botox tends to be sudden. Depending on what works best for you, this can make a difference when you're deciding.

Molecular Size

Dysport has smaller molecules compared to Botox, which means it diffuses more and spreads out over a broader area. This can be beneficial when treating larger areas, such as the forehead.


The formula of Dysport is more diluted than Botox, so their dosage level may not interchangeable. It also means a greater number of units may be needed when using Dysport than with Botox, but higher dilution doesn’t mean lesser efficacy.


Compared to Botox, Dysport diffuses more and easily spreads to a broader area when injected. When addressing large areas, Dysport may be more cost-effective because fewer injections will be necessary to target these areas. On the other hand, it may not be as effective in treating smaller areas, and risk of migration may also be higher.


There is no substantial proof of which product lasts the longest. Botulinum toxin type A injectables generally last within 3–6 months. A small study revealed that Botox may last longer than Dysport, but a larger study disputed this claim. Among 180 patients treated, both brands have shown similar duration of effects.

If your patients are looking for botulinum toxin injections, it is likely the deciding factor will be the cost. Dysport costs slightly less than Botox. Discuss the options with your patients, so they can make an informed decision about their treatment.

Conclusion ~ What Our Staff Likes Best

Our team is divided! We have staff members that like one more than the other on both sides for the reasons we've listed. What's your favorite?

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